Home
About the Program
Structure
Calendar 2017
Calendar 2016
Calendar 2015
Calendar 2014
Calendar 2013
Calendar 2012
Calendar 2011
Admissions
The Students
Research and Faculty
Coordinating Committee
Module Coordinators
Publications
PhD Degrees Completed
Events and Highlights
Contacts
Reserved Area
Forgot your password?
Staff
Name
Carmo, Alexandre
E-Mail
acarmo@ibmc.up.pt
Position
Principal Investigator; GABBA Director
Institution
IBMC/ICBAS
City
Porto
Country
Portugal
Field of Research
Signal Transduction, Molecular Immunology

Relevant Publications
James JR, Oliveira MI, Carmo AM, Iaboni A, Davis SJ (2006) A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer. Nat. Methods 3:1001-1006.
Castro MAA, Oliveira MI, Nunes RJ, Fabre S, Barbosa R, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM (2007) Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. J. Immunol. 178:4351-4361.
Fernandes RA, Yu C, Carmo AM, Evans EJ, van der Merwe PA, Davis SJ (2010) What controls T cell receptor phosphorylation? Cell 142:668-669.
Pinto PAB, Henriques T, Freitas MO, Martins T, Domingues RG, Wyrzykowska PS, Coelho PA, Carmo AM, Sunkel CE, Proudfoot NJ, Moreira A (2011) RNA polymerase II kinetics in polo polyadenylation signal selection. EMBO J. in press.

Publications
Evans EJ, Castro MAA, O’Brien R, Kearney A, Walsh H, Sparks LM, Tucknott MG, Davies EA, Carmo AM, van der Merwe PA, Stuart DI, Jones EY, Ladbury JE, Ikemizu S, Davis SJ (2006) Crystal structure and binding properties of the CD2 and CD244 (2B4)-binding protein, CD48. J. Biol. Chem. 281:29309-29320.
Kearney A, Avramovic A, Castro MAA, Carmo AM, Davis SJ, van der Merwe PA (2007) CD2 binding to CD58 is accompanied by energetically significant conformational adjustments and is accelerated by electrostatic interactions. J. Biol. Chem. 282:13160-13166.
Nunes RJ, Castro MAA, Gonçalves CM, Bamberger M, Pereira CF, Bismuth G, Carmo AM (2008) Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2. J. Immunol. 180:988-997.
Coelho PA, Queiroz-Machado J, Carmo AM, Moutinho-Pereira S, Maiato H, Sunkel CE (2008) Dual role of Topoisomerase II in centromere resolution and Aurora B activity. PLoS Biol. 6:1758-1777.
Gonçalves CM, Castro MAA, Henriques T, Oliveira MI, Pinheiro HC, Oliveira C, Sreenu VB, Evans EJ, Davis SJ, Moreira A, Carmo AM (2009) Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Mol. Immunol. 46:2585-2596.
INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology