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Publications

Students - Recent Publications
Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor KR, Bjerke L, Clarke M, Vinci M, Nandhabalan M, Temelso S, Popov S, Molinari V, Raman P, Waanders AJ, Han HJ, Gupta S, Al-Sarraj S, Chandler C, Ng HK, Li X, Mu K, Trabelsi S, Brahim DH, Kisljakov AN, Konovalov DM, Moore AS, Carcaboso AM, Sunol M, de Torres C, Cruz O, Mora J, Shats LI, Stavale JN, Bidinotto LT, Reis RM, Entz-Werle N, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Monje M, Jabado N, Baker SJ, Pfister SM, Jones DTW, Fouladi M, von Bueren AO, Baudis M, Resnick A, Jones C. Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. Cancer Cell. 2017 Oct 9;32(4):520-537.e5.
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Resende LP, Truong ME, Gomez A, Jones DL. Intestinal stem cell ablation reveals differential requirements for survival in response to chemical challenge, Dev Biol. 2017 Apr 1;424(1):10-17
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"Declining Transmission and Immunity to Malaria and Emerging Artemisinin Resistance in Thailand: A Longitudinal Study."
Ataíde R, Powell R, Moore K, McLean A, Phyo AP, Nair S, White M, Anderson TJ, Beeson JG, Simpson JA, Nosten F, Fowkes FJI. (2017) Journal of Infectious Diseases
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Flavia Sousa, Pedro Fonte, Andrea Cruz, Peter J. Kennedy, Inês M. Pinto, Bruno Sarmento. Polyester-Based Nanoparticles for the Encapsulation of Monoclonal Antibodies. In: Picanço-Castro V., Swiech K. (eds) Recombinant Glycoprotein Production. Methods in Molecular Biology, 2018 vol 1674. Humana Press, New York, NY
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Helena S. Domingues, Andrea Cruz, Jonah R. Chan, João B. Relvas, Boris Rubinstein, Inês Mendes Pinto. Mechanical plasticity during oligodendrocyte differentiation and myelination, Glia. 1–10
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Flávia Sousa, Andrea Cruz, Pedro Fonte, Inês Mendes Pinto, Maria Teresa Neves-Petersen, Bruno Sarmento. A new paradigm for antiangiogenic therapy through controlled release of bevacizumab from PLGA nanoparticles. Scientific Reports Jun 16;7(1):3736
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Sandra O. Braz*, Andrea Cruz*, Andrea Lobo*, Joana Bravo, Joana Moreira-Ribeiro, Isabel Pereira-Castro, Jaime Freitas, Joao B. Relvas, Teresa Summavielle, Alexandra Moreira. Expression of Rac1 alternative 3`UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons. BBA Gene Regulatory Mechanisms (2017), doi:10.1016/j.bbagrm.2017.03.002. * These authors contribute equally to the work
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Bucher, M., Wolfowicz, I., Voss, P. A., Hambleton, E. A., Guse, A. (2016). Development and symbiosis establishment in the cnidarian endosymbiosis model Aiptasia sp. Sci. Rep., 6: 19867.
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Grawunder, D., Hambleton, E. A., Bucher, M., Wolfowicz, I., Bechtoldt, N., Guse, A. (2015). Induction of gametogenesis in the cnidarian endosymbiosis model Aiptasia sp. Sci. Rep., 5: 15677.
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Gonçalves E, Fragoulis A, Garcia-Alonso L, Cramer T, Saez-Rodriguez J, Beltrao P Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer. Cell Systems 2017
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Staff - Recent Publications
Pinto PAB, Henriques T, Freitas MO, Martins T, Domingues RG, Wyrzykowska PS, Coelho PA, Carmo AM, Sunkel CE, Proudfoot NJ, Moreira A (2011) RNA polymerase II kinetics in polo polyadenylation signal selection. EMBO J. in press.
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Fernandes RA, Yu C, Carmo AM, Evans EJ, van der Merwe PA, Davis SJ (2010) What controls T cell receptor phosphorylation? Cell 142:668-669.
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Gonçalves CM, Castro MAA, Henriques T, Oliveira MI, Pinheiro HC, Oliveira C, Sreenu VB, Evans EJ, Davis SJ, Moreira A, Carmo AM (2009) Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Mol. Immunol. 46:2585-2596.
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Coelho PA, Queiroz-Machado J, Carmo AM, Moutinho-Pereira S, Maiato H, Sunkel CE (2008) Dual role of Topoisomerase II in centromere resolution and Aurora B activity. PLoS Biol. 6:1758-1777.
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Nunes RJ, Castro MAA, Gonçalves C, Bamberger M, Pereira CF, Bismuth G, Carmo AM (2008) Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2. J. Immunol. 180:988-997.
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Carneiro F, Oliveira C, Suriano G, Seruca R: Molecular pathology of familial gastric cancer, with an emphasis on Hereditary Diffuse Gastric Cancer (HDGC).

J Clin Pathol 61:25-30, 2008. DOI:10.1136jcp.2006.043679.
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Nunes RJ, Castro MAA, Gonçalves CM, Bamberger M, Pereira CF, Bismuth G, Carmo AM (2008) Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2. J. Immunol. 180:988-997.
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Kearney A, Avramovic A, Castro MAA, Carmo AM, Davis SJ, van der Merwe PA (2007) CD2 binding to CD58 is accompanied by energetically significant conformational adjustments and is accelerated by electrostatic interactions. J. Biol. Chem. 282:13160-13166.
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Kearney A, Avramovic A, Castro MAA, Carmo AM, Davis SJ, van der Merwe PA (2007) CD2 binding to CD58 is accompanied by energetically significant conformational adjustments and is accelerated by electrostatic interactions. J. Biol. Chem. 282:13160-13166.
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Castro MAA, Oliveira MI, Nunes RJ, Fabre S, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM (2007) Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. J. Immunol. 178:4351-4361.
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INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology