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About the PhD |
Date of Thesis Defence |
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Relevant Publications |
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James JR, Oliveira MI, Carmo AM, Iaboni A, Davis SJ (2006) A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer. Nat. Methods 3:1001-1006. |
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Castro MAA, Oliveira MI, Nunes RJ, Fabre S, Barbosa R, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM (2007) Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. J. Immunol. 178:4351-4361. |
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Fernandes RA, Yu C, Carmo AM, Evans EJ, van der Merwe PA, Davis SJ (2010) What controls T cell receptor phosphorylation? Cell 142:668-669. |
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Pinto PAB, Henriques T, Freitas MO, Martins T, Domingues RG, Wyrzykowska PS, Coelho PA, Carmo AM, Sunkel CE, Proudfoot NJ, Moreira A (2011) RNA polymerase II kinetics in polo polyadenylation signal selection. EMBO J. in press. |
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Huntsman DG, Carneiro F, Lewis FR, MacLeod PM, Hayashi A, Monaghan KG, Maung R, Seruca R, Jackson CE, Caldas C: Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations.
N Engl J Med 344:1904-1909, 2001. |
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Nunes RJ, Castro MAA, Gonçalves C, Bamberger M, Pereira CF, Bismuth G, Carmo AM (2008) Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2. J. Immunol. 180:988-997. |
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Kearney A, Avramovic A, Castro MAA, Carmo AM, Davis SJ, van der Merwe PA (2007) CD2 binding to CD58 is accompanied by energetically significant conformational adjustments and is accelerated by electrostatic interactions. J. Biol. Chem. 282:13160-13166. |
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Castro MAA, Oliveira MI, Nunes RJ, Fabre S, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM (2007) Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. J. Immunol. 178:4351-4361. |
View Publication |
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James JR, Oliveira MI, Carmo AM, Iaboni A, Davis SJ (2006) A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer. Nat. Methods 3:1001-1006. |
View Publication |
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Evans EJ, Castro MAA, O?Brien R, Kearney A, Walsh H, Sparks LM, Tucknott MG, Davies EA, Carmo AM, van der Merwe PA, Stuart DI, Jones EY, Ladbury JE, Ikemizu S, Davis SJ (2006) Crystal structure and binding properties of the CD2 and CD244 (2B4)-binding protein, CD48. J. Biol. Chem. 281:29309-29320. |
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Oliveira C, de Bruin J, Nabais S, Ligtenberg M, Moutinho C, Nagengast FM, Seruca R, van Krieken H, Carneiro F:
Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in a HDGC tumour.
Oncogene 23:2236-2240, 2004. DOI: 10.1038sj.onc.1207335 |
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Carneiro F, Huntsman D, Smyrk T, Owen DA, Seruca R, Pharoah P, Caldas C, Manuel Soinho-Simões M: Model of early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening.
J Pathol 203: 681-687, 2004. DOI: 10.1002path.1564 |
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Carneiro F, Chaves P: Pathologic risk factors for therapy for adenocarcinoma of the gastric cardia and gastroesophageal junction.
Surg Oncol Clin North Am 15(4): 697-714, 2006. DOI: 10.1016j.soc.2006.07.012 |
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Carneiro F, Oliveira C, Suriano G, Seruca R: Molecular pathology of familial gastric cancer, with an emphasis on Hereditary Diffuse Gastric Cancer (HDGC).
J Clin Pathol 61:25-30, 2008. DOI:10.1136jcp.2006.043679. |
View Publication |
Publications |
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Evans EJ, Castro MAA, O’Brien R, Kearney A, Walsh H, Sparks LM, Tucknott MG, Davies EA, Carmo AM, van der Merwe PA, Stuart DI, Jones EY, Ladbury JE, Ikemizu S, Davis SJ (2006) Crystal structure and binding properties of the CD2 and CD244 (2B4)-binding protein, CD48. J. Biol. Chem. 281:29309-29320. |
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Kearney A, Avramovic A, Castro MAA, Carmo AM, Davis SJ, van der Merwe PA (2007) CD2 binding to CD58 is accompanied by energetically significant conformational adjustments and is accelerated by electrostatic interactions. J. Biol. Chem. 282:13160-13166. |
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Nunes RJ, Castro MAA, Gonçalves CM, Bamberger M, Pereira CF, Bismuth G, Carmo AM (2008) Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2. J. Immunol. 180:988-997. |
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Coelho PA, Queiroz-Machado J, Carmo AM, Moutinho-Pereira S, Maiato H, Sunkel CE (2008) Dual role of Topoisomerase II in centromere resolution and Aurora B activity. PLoS Biol. 6:1758-1777. |
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Gonçalves CM, Castro MAA, Henriques T, Oliveira MI, Pinheiro HC, Oliveira C, Sreenu VB, Evans EJ, Davis SJ, Moreira A, Carmo AM (2009) Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Mol. Immunol. 46:2585-2596. |
The responsibility for this page contents is entirely of the student/alumnus. |
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Program financially supported by
the National Foundation for
Science and Technology
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