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Class of 2005
Name
Coelho, Miguel
E-Mail
mbcoelho@gmail.com
1st Degree
Biology
University (1st Degree)
Universidade de Lisboa
About the PhD
Field of Research
RNA biology
Thesis Title
Mechanism of Splicing Regulation by PTB minimal repressor domain
Abstract
Alternative splicing can generate different mRNAs from a single gene, and is the major contributor to protein diversity in higher eukaryotes. Regulation of alternative splicing occurs mainly through the action of trans-acting...
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Supervisor(s)
Prof. Chris Smith
University
University of Cambridge
Laboratory
Department of Biochemistry
City
Cambridge
Country
UK
Date of Thesis Defence
2010-07-14
After the PhD (Current Situation)
Position
Post-doc
Project
Functional interactions between PTB RRM2 and co-regulators
Institution
University of Cambridge
View Institution website
City
Cambridge
Country
UK

Relevant Publications
Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses
View Publication
Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing
View Publication
In vivo requirement of the small subunit of U2AF for recognition of a weak splice site
View Publication
Last Update
2013-03-14 12:14:31
INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology