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| Name |
| Guedes de Melo, Sónia |
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| Nationality |
| Portuguese |
| E-Mail |
| soniagmelo@gmail.com |
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| 1st Degree |
| Biochemistry |
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| University (1st Degree) |
| FCUP |
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| About the PhD |
| Field of Research |
| microRNAs biogenesis |
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| Thesis Title |
| MicroRNA machinery in human cancers |
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| Supervisor(s) |
| Doctor Manel Esteller, MD, PhD CNIO-Madrid / ICO-Barcelona |
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| Co-Supervisor(s) |
| Fátima Carneiro, MD, PhD, HGSJ and IPATIMUP - Porto Carla Oliveira, PhD, IPATIMUP - Porto |
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| University |
| University of Porto |
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| Laboratory |
| Epigenetics lab |
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| City |
| Madrid and Barcelona |
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| Country |
| Spain |
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| Date of Thesis Defence |
| 2010-04-13 |
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| After the PhD (Current Situation) |
| Position |
| EMBO Post doctoral fellow |
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| Project |
| MicroRNA biogenesis crosstalk on fibroblast reprogramming |
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| Institution |
| Harvard Medical School |
| View Institution website |
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| City |
| Boston |
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| Country |
| USA |
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| Relevant Publications |
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A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nature Genetics
Sonia A Melo, Santiago Ropero, Catia Moutinho, Lauri A Aaltonen, Hiroyuki Yamamoto, George A Calin, Simona Rossi, Agustin F Fernandez, Fatima Carneiro, Carla Oliveira, Bibiana Ferreira, Chang-Gong Liu, Alberto Villanueva, Gabriel Capella, Simo Schwartz Jr, Ramin Shiekhattar & Manel Esteller |
| View Publication |
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Dysregulation of microRNAs in cancer: Playing with fire. FEBS Let
Sonia A. Melo, Manel Esteller |
| View Publication |
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A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells. Cancer Cell
Sonia A. Melo, Catia Moutinho, Santiago Ropero, George A. Calin, Simona Rossi, Riccardo Spizzo, Agustin F. Fernandez, Veronica Davalos, Alberto Villanueva, Guillermo Montoya, Hiroyuki Yamamoto, Simo Schwartz and Manel Esteller |
| View Publication |
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Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. PNAS
Sonia Melo, Alberto Villanueva, Catia Moutinho, Veronica Davalos, Riccardo Spizzo, Cristina Ivan, Simona Rossi, Fernando Setien, Oriol Casanovas, Laia Simo-Riudalbas, Javier Carmona, Jordi Carrere, August Vidale, Alvaro Aytes, Sara Puertas, Santiago Ropero, Raghu Kallurig, Carlo M. Croce, George A. Calin, and Manel Esteller |
| View Publication |
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A precursor microRNA in a cancer cell nucleus: Get me out of here! Cell Cycle
Melo SA, Esteller M. |
| View Publication |
| Publications |
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The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer. Genome Research
Fernandez AF, Rosales C, Lopez-Nieva P, Graña O, Ballestar E, Ropero S, Espada J, Melo SA, Lujambio A, Fraga MF, Pino I, Javierre B, Carmona FJ, Acquadro F, Steenbergen RD, Snijders PJ, Meijer CJ, Pineau P, Dejean A, Lloveras B, Capella G, Quer J, Buti M, Esteban JI, Allende H, Rodriguez-Frias F, Castellsague X, Minarovits J, Ponce J, Capello D, Gaidano G, Cigudosa JC, Gomez-Lopez G, Pisano DG, Valencia A, Piris MA, Bosch FX, Cahir-McFarland E, Kieff E, Esteller M. |
| View Publication |
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CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer. Oncogene
Lujambio A, Portela A, Liz J, Melo SA, Rossi S, Spizzo R, Croce CM, Calin GA, Esteller M. |
| View Publication |
| The responsibility for this page contents is entirely of the student/alumnus. |
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Program financially supported by
the National Foundation for
Science and Technology
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