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Class of 2008
Name
Curado, João
Nationality
Portuguese
E-Mail
Joao.curado@crg.eu
Master Degree
Bioinformatics
About the PhD
Field of Research
Bioinformatics & Genomics
Thesis Title
Chromatin: new insights into splicing
Abstract
Chromatin states have been characterized with great detail. Here we explored transcription of developmental regulated genes in the context of chromatin. We found that these genes are expressed in the absence of canonically...
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Supervisor(s)
Roderic Guigó
Co-Supervisor(s)
Alexandra Moreira
University
Universidade do Porto | Centre de Regulaciò Genómica
Laboratory
Computational biology of RNA processing
City
Barcelona
Country
Spain
Date of Thesis Defence
2015-11-20
After the PhD (Current Situation)
Position
CEO and Bioinformatics researcher
Project
Plasma RNA sequencing for diagnostics
Institution
Flomics & CRG
View Institution website
City
Barcelona
Country
Spain

Relevant Publications
Pérez-Lluch S*, Blanco E*, Tilgner H*, Curado J*, Ruiz-Romero M, Corominas M, Guigó, R Absence of canonical marks of active chromatin in developmentally regulated genes
Nature Genetics 47, 1158–1167 (2015) doi:10.1038/ng.3381
View Publication
Curado J, et al. Promoter-like epigenetic signatures in exons displaying cell type-specific splicing
Genome Biology 2015, 16:236 doi:10.1186/s13059-015-0797-8
View Publication

Publications
Tilgner H, Knowles DG, Johnson R, Davis CA, Chakrabortty S, Djebali S, Curado J, Snyder M, Gingeras TR, Guigó R.
Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs
Genome Res. 2012 Sep;22(9):1616-25.
View Publication
Sarah Djebali, et al.
Landscape of transcription in human cells
Nature. 2012 Sep 6;489(7414):101-8. doi: 10.1038/nature11233.
View Publication
Last Update
2015-12-07 17:07:29
INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology