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Class of 2008
Name
Saleiro, Diana
Nationality
Portuguese
E-Mail
dianasaleiro@gmail.com
1st Degree
Licenciatura: Biology
University (1st Degree)
Faculdade de Ciencias da Universidade do Porto
About the PhD
Field of Research
Cancer Research
Thesis Title
MOLECULAR MECHANISMS OF ESTROGEN RECEPTOR BETA ACTION IN COLORECTAL CARCINOGENESIS
Abstract
Colorectal cancer (CRC) is a major public health problem in the world population, which emphasizes the need to study novel molecular targets in order to develop alternative chemopreventive and chemotherapeutic strategies...
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Supervisor(s)
Dr. Rajendra G. Mehta
University
Illinois Institute of Technology
Laboratory
Cancer Biology Division, IIT Research Institute
City
Chicago
Country
USA
Date of Thesis Defence
2013-07-31
After the PhD (Current Situation)
Position
Post-doctoral fellow
Project
Definition of cellular signaling pathways regulated by interferon receptors
Institution
Northwestern University - Robert H. Lurie Comprehensive Cancer Center
City
Chicago
Country
USA

Relevant Publications
Saleiro D, Murillo G, Lubahn DB, Kopelovich L, Korach KS, Mehta RG. Enhanced induction of mucin-depleted foci in estrogen receptor {beta} knockout mice. Cancer Prev Res (Phila). 2010;3:1198-204.
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Saleiro D, Murillo G, Benya RV, Bissonnette M, Hart J, Mehta RG.
Estrogen receptor-β protects against colitis-associated neoplasia in mice. Int J Cancer. 2012;131:2553-61. doi: 10.1002/ijc.27578.
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Saleiro D, Platanias LC. Intersection of mTOR and STAT signaling in immunity. Trends Immunol. 2015 Jan;36(1):21-9.
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Saleiro D, Mehrotra S, Kroczynska B, Beauchamp EM, Lisowski P, Majchrzak-Kita B, Bhagat TD, Stein BL, McMahon B, Altman JK, Kosciuczuk EM, Baker DP, Jie C, Jafari N, Thompson CB, Levine RL, Fish EN, Verma AK, Platanias LC. Central role of ULK1 in type I interferon signaling. Cell Rep. 2015 Apr 28;11(4):605-17.
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Saleiro D, Kosciuczuk EM, Platanias LC. Beyond autophagy: New roles for ULK1 in immune signaling and interferon responses. Cytokine Growth Factor Rev. 2016 Jun;29:17-22.
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Kosciuczuk EM, Saleiro D, Kroczynska B, Beauchamp EM, Eckerdt F, Blyth GT, Abedin SM, Giles FJ, Altman JK, Platanias LC. Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo. Blood. 2016 Jul 21;128(3):410-4.
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Arslan AD, Sassano A, Saleiro D, Lisowski P, Kosciuczuk EM, Fischietti M, Eckerdt F, Fish EN, Platanias LC. Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma. Oncogene. 2017 Jul 3.
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Publications
Swarup VP, Huang Y, Murillo G, Saleiro D, Mehta RG, Bishnoi SW. Modeling the cellular impact of nanoshell-based biosensors using mouse alveolar macrophage cultures. Metallomics. 2011 Nov;3(11):1218-26. doi: 10.1039/c1mt00089f.
Mazué F, Delmas D, Murillo G, Saleiro D, Limagne E, Latruffe N. Differential protective effects of red wine polyphenol extracts (RWEs) on colon carcinogenesis. Food Funct. 2014 Apr;5(4):663-70.
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Sakamoto KM, Grant S, Saleiro D, Crispino JD, Hijiya N, Giles F, Platanias LC, Eklund EA. Targeting novel signaling pathways for resistant acute myeloid leukemia. Mol Genet Metab. 2015 Mar;114(3):397-402.
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Colamonici M, Blyth G, Saleiro D, Szilard A, Bliss-Moreau M, Giles FJ, Altman JK, Beauchamp EM, Platanias LC. Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase. Oncotarget. 2015 Apr 10;6(10):8062-70.
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Saleiro D, Platanias LC. ULK1 in type I interferon response. Oncotarget. 2015 Sep 22;6(28):24586-7.
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[more publications]
Last Update
2017-10-06 22:21:11

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