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Class of 2009
Name
Sin, Olga
Nationality
Portuguese
E-Mail
olga.sin@mpi-muenster.mpg.de
1st Degree
Cellular and Molecular Biology
University (1st Degree)
Universidade Nova de Lisboa
Master Degree
Neurosciences
University (Master Degree)
Universidade de Lisboa
About the PhD
Field of Research
Neurosciences
Thesis Title
Aggregation-promoting factors in neurodegenerative diseases: Insights from a C. elegans model
Abstract
Neurodegenerative diseases are complex human diseases that are still poorly understood in terms of their etiology and pathogenesis. The objective of this work is to zoom in on the molecular and cellular events that lead to...
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Supervisor(s)
Prof. Dr. Ellen Nollen; Dr. Victor Guryev
Co-Supervisor(s)
Prof. Dr. João Bettencourt Relvas
University
University Medical Center Groningen, The Netherlands and Instituto de Ciências Biomédicas de Abel Salazar, Portugal
City
Groningen
Country
The Netherlands
Date of Thesis Defence
2016-01-13
After the PhD (Current Situation)
Position
Junior Postdoc
Project
Elucidating the role of transfer RNAs in protein quality control
Institution
Max Planck Institute for Molecular Biomedicine
View Institution website
City
Münster
Country
Germany

Relevant Publications
Olga Sin, Tristan de Jong, Alejandro Mata-Cabana, Michelle Kudron, Mohamad Amr Zaini, Francesco A. Aprile, Renée I. Seinstra, Esther Stroo, Roméo Willinge Prins, Céline N. Martineau, Hai Hui Wang, Wytse Hogewerf, Anne Steinhof, Erich E. Wanker, Michele Vendruscolo, Cornelis F. Calkhoven, Valerie Reinke, Victor Guryev, and Ellen A.A. Nollen. 2017 Molecular Cell 65, 1096–1108.
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Publications
Sin O, Michels H, Nollen EAA. Genetic screens in Caenorhabditis elegans models for neurodegenerative diseases. Biochim Biophys Acta. 2014 Oct;1842(10):1951-1959. doi: 10.1016/j.bbadis.2014.01.015. Epub 2014 Feb 11.
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Sin O and Nollen EAA. Regulation of protein homeostasis in aging and aging-related diseases: role of coding and non-coding genes. Cell Mol Life Sci. 2015 Nov;72(21):4027-47. doi: 10.1007/s00018-015-1985-0. Epub 2015 Jul 21.
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Last Update
2017-03-16 16:58:25

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Program financially supported by
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Science and Technology