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Class of 2015
Soares da Silva, Francisca
1st Degree
Biomedical Pharmacy
University (1st Degree)
Master Degree
Biomedical Research
University (Master Degree)
About the PhD
Field of Research
Developmental Biology & Immunology
Thesis Title
Environmental Signals Driving the Onset of Hematopoiesis in the Fetal Liver
Hematopoiesis occurs in specialized organs and the role of the environment in the behavior of hematopoietic progenitors is increasingly recognized. There is compelling evidence that the major hematopoietic supportive stromal...
Perpétua Pinto-do-Ó & Ana Cumano
INEB/i3S, Porto, Portugal & Institut Pasteur, Paris, France
Date of Thesis Defence

Relevant Publications
Soares-da-Silva Francisca*, Peixoto Márcia*, Cumano Ana, Pinto-do-Ó Perpetua. Crosstalk Between the Hepatic and Hematopoietic Systems During Embryonic Development 2020 Frontiers in Cell and Developmental Biology doi: 10.3389/fcell.2020.00612
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Elsaid Ramy*, Soares-da-Silva Francisca*, Peixoto Marcia, Amiri Dali, Mackowski Nathan, Pereira Pablo, Bandeira Antonio, Cumano Ana. Hematopoiesis: A Layered Organization Across Chordate Species 2020 Frontiers in Cell and Developmental Biology doi:10.3389/fcell.2020.606642
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Soares-da-Silva F, Freyer L, Elsaid R, Burlen-Defranoux O, Iturri L, Sismeiro O, Pinto-do-Ó P, Gomez-Perdiguero E, Cumano A. Yolk sac, but not HSC-derived progenitors, sustain erythropoiesis throughout murine embryonic life 2021 J. Exp. Medicine. 218(4); doi: 10.1084/jem.20201729
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Freire AG, Waghray A, Soares-da-Silva F, Resende TP, Lee DF, Pereira CF, Nascimento DS, Lemischka IR, and Pinto-do-Ó P. (2017) Transient HES5 activity instructs mesodermal cells toward a cardiac fate. Stem Cell Reports. 9(1), 136-148.
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Valente M, Resende TP, Nascimento DS, Burlen-Defranoux O, Soares-da-Silva F, et al. (2019) Mouse HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury. PLOS Biology 17(6): e3000335. https://doi.org/10.1371/journal.pbio.3000335
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Ramy Elsaid, Sylvain Meunier, Odile Burlen-Defranoux, Francisca Soares-da-Silva, Thibaut Perchet, Lorea Iturri, Laina Freyer, Paulo Vieira, Pablo Pereira, Rachel Golub, Antonio Bandeira, Elisa Gomez Perdiguero, Ana Cumano; A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner. Blood blood.2020006779.
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Last Update
2020-12-21 10:47:39

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