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Class of 1999
Name
Carvalho, Pedro
E-Mail
pedro.carvalho@path.ox.ac.uk
About the PhD
Field of Research
Cell Biology
Thesis Title
Function and mechanisms of microtubule plus-end tracking proteins
Supervisor(s)
David Pellman, M.D., Ph.D.
Co-Supervisor(s)
Claudio Sunkel, Ph.D.
University
ICBAS-UP
Laboratory
Dana Farber Cancer Institute
City
Boston
Country
USA
Date of Thesis Defence
2005-04-08
After the PhD (Current Situation)
Position
EP Abraham Professor of Cell biology
Institution
Sir William Dunn School of pathology- University of Oxford
View Institution website
City
Oxford
Country
UK

Relevant Publications
Carvalho P, Stanley AM, Rapoport TA.
Retro-translocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell; 2010: 143 (4) 579-591
Carvalho P, Goder V, Rapoport TA. Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell. 2006 Jul 28;126(2):361-73.
Carvalho P, Gupta Jr ML, Hoyt MA, Pellman D. Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell. 2004 Jun;6(6):815-29.
Carvalho P, Tirnauer JS, Pellman D. Surfing on microtubule ends. Trends Cell
Biol. 2003 May;13(5):229-37.
Lin H, Carvalho P, Kho D, Tai C, Pierre P, Fink GR, Pellman D. Polyploids Require Bik1p for Kinetochore-Microtubule Attachment. J Cell Biol. 2001 Dec 24;155(7):1173-84;  equal contribution.

Publications
Goder V, Carvalho P, Rapoport TA.
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p. FEBS Lett; 2008: 582 (11) 1575 - 1580
Gupta ML Jr, Carvalho P, Roof DM, Pellman D. Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle.
Nat Cell Biol. 2006 Sep;8(9):913-23.
Carvalho P, Pellman D. Mitotic spindle: laser microsurgery in yeast cells. Curr Biol. 2004 Sep 21;14(18):R748-50.
Sheeman B, Carvalho P, Sagot I, Geiser J, Kho D, Hoyt MA, Pellman D. Determinants of S. cerevisiae Dynein Localization and Activation: Implications for the Mechanism of Spindle Positioning. Curr Biol. 2003 Mar 4;13(5):364-72.
Last Update
2017-11-09 15:15:29

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