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| Name |
| Carvalho, Pedro |
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| E-Mail |
| pedro.carvalho@path.ox.ac.uk |
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| About the PhD |
| Field of Research |
| Cell Biology |
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| Thesis Title |
| Function and mechanisms of microtubule plus-end tracking proteins |
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| Supervisor(s) |
| David Pellman, M.D., Ph.D. |
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| Co-Supervisor(s) |
| Claudio Sunkel, Ph.D. |
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| University |
| ICBAS-UP |
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| Laboratory |
| Dana Farber Cancer Institute |
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| City |
| Boston |
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| Country |
| USA |
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| Date of Thesis Defence |
| 2005-04-08 |
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| After the PhD (Current Situation) |
| Position |
| EP Abraham Professor of Cell biology |
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| Institution |
| Sir William Dunn School of pathology- University of Oxford |
| View Institution website |
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| City |
| Oxford |
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| Country |
| UK |
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| Relevant Publications |
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Carvalho P, Stanley AM, Rapoport TA.
Retro-translocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell; 2010: 143 (4) 579-591
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| Carvalho P, Goder V, Rapoport TA. Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell. 2006 Jul 28;126(2):361-73. |
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| Carvalho P, Gupta Jr ML, Hoyt MA, Pellman D. Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell. 2004 Jun;6(6):815-29. |
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Carvalho P, Tirnauer JS, Pellman D. Surfing on microtubule ends. Trends Cell
Biol. 2003 May;13(5):229-37.
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| Lin H, Carvalho P, Kho D, Tai C, Pierre P, Fink GR, Pellman D. Polyploids Require Bik1p for Kinetochore-Microtubule Attachment. J Cell Biol. 2001 Dec 24;155(7):1173-84; equal contribution. |
| Publications |
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Goder V, Carvalho P, Rapoport TA.
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p. FEBS Lett; 2008: 582 (11) 1575 - 1580
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Gupta ML Jr, Carvalho P, Roof DM, Pellman D. Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle.
Nat Cell Biol. 2006 Sep;8(9):913-23.
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| Carvalho P, Pellman D. Mitotic spindle: laser microsurgery in yeast cells. Curr Biol. 2004 Sep 21;14(18):R748-50. |
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| Sheeman B, Carvalho P, Sagot I, Geiser J, Kho D, Hoyt MA, Pellman D. Determinants of S. cerevisiae Dynein Localization and Activation: Implications for the Mechanism of Spindle Positioning. Curr Biol. 2003 Mar 4;13(5):364-72. |
| Last Update |
| 2017-11-09 15:15:29 |
| The responsibility for this page contents is entirely of the student/alumnus. |
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Program financially supported by
the National Foundation for
Science and Technology
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