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Class of 1999
Name
Silva, Raquel M.
Nationality
Portuguese
E-Mail
raquels@ipatimup.pt
1st Degree
Biology
University (1st Degree)
University of Aveiro
About the PhD
Field of Research
Molecular Biology, Evolution, Proteostasis
Thesis Title
Molecular reconstruction of a genetic code alteration.
Abstract
Several Candida species translate the standard leucine CUG codon as serine. This genetic code alteration is mediated by a novel tRNA (ser-tRNACAG), which can be charged both with serine (97 %) and leucine (3%) in vivo. Therefore,...
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Supervisor(s)
Manuel Santos
University
University of Aveiro
Laboratory
RNA lab, U. Aveiro / IBGC, CNRS Bordeaux / Genomics Lab, UMC Utrecht.
City
Aveiro
Country
Portugal
Date of Thesis Defence
2005-10-11
After the PhD (Current Situation)
Position
Assistant Researcher
Institution
IEETA
View Institution website
City
Aveiro
Country
Portugal

Relevant Publications
Carneiro J, Duarte-Pereira S, Azevedo L, Castro LFC, Aguiar P, Moreira IS, Amorim A, Silva RM (2013). The Evolutionary Portrait of Metazoan NAD Salvage. PLoS ONE 8(5): e64674.
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Duarte-Pereira S, Silva SS, Azevedo L, Castro L, Amorim A, Silva RM (2014).
NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples. Scientific Reports 4: 6311.
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RM Silva, D Pratas, L Castro, AJ Pinho, PJSG Ferreira (2015). Three minimal sequences found in Ebola virus genomes and absent from human DNA. Bioinformatics: btv189.
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Pratas D, Silva RM, Pinho AJ, Ferreira PJSG (2015). An alignment-free method to find and visualise rearrangements between pairs of DNA sequences. Sci Rep. 5: 10203.
View Publication

Publications
RM Silva, et al. (2009). The Yeast PNC1 Longevity Gene Is Up-Regulated by mRNA Mistranslation. PLoS ONE. 4(4): e5212.
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S Costa-de-Oliveira et al. (2011). FKS2 Mutations Associated with Decreased Echinocandin Susceptibility of Candida glabrata following Anidulafungin Therapy. Antimicrobial Agents and Chemotherapy 55(3):1312-4. Epub 2010 Dec 13.
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A Moleirinho, et al. (2011). Gains, losses and changes of function after gene duplication: study of the metallothionein family. PLoS ONE 6(4): e18487.
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AP Silva, et al. Transcriptional profiling of azole-resistant Candida parapsilosis strains. Antimicrob. Agents Chemother. 55(7): 3546-56. Epub 2011 Apr 25.
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Raquel M. Silva, et al. (2007). Critical roles for a genetic code alteration in the evolution of the genus Candida. EMBO J. 26(21): 4555-65.
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[more publications]
Last Update
2015-05-25 17:44:50
INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology