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Class of 2000
Name
Teixeira, Ana
E-Mail
teixeira@well.ox.ac.uk
1st Degree
Biology
University (1st Degree)
FCUP
About the PhD
Field of Research
Human Genetics
Thesis Title
MUC1 polymorphism in relation to susceptibility to Helicobacter pylori gastritis
Supervisor(s)
Dallas Swallow
Co-Supervisor(s)
Leonor David
University
University College London
Laboratory
The Galton Laboratory
City
London
Country
United Kingdom
Date of Thesis Defence
2005-11-29
After the PhD (Current Situation)
Position
Postdoctoral Research Associate
Project
Profiling of transcription factor binding sites applying high throughput platforms to the study of Protein-DNA interactions
Institution
The Wellcome Trust Centre for Human Genetics, University of Oxford
City
Oxford
Country
United Kingdom

Relevant Publications
Broderick P, Carvajal-Carmona L, Pittman AM, Webb E, Howarth K, Rowan A, Lubbe S, Spain S, Sullivan K, Fielding S, Jaeger E, Vijayakrishnan J, Kemp Z, Gorman M, Chandler I, Papaemmanuil E, Penegar S, Wood W, Sellick G, Qureshi M, Teixeira A, Domingo E, Barclay E, Martin L, Sieber O; CORGI Consortium, Kerr D, Gray R, Peto J, Cazier JB, Tomlinson I, Houlston RS. (2007) A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet 39(11):1315-7
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.Houlston RS, Webb E, Broderick P, Pittman AM, Di Bernardo MC, Lubbe S, Chandler I, Vijayakrishnan J, Sullivan K, Penegar S; Colorectal Cancer Association Study Consortium, Carvajal-Carmona L, Howarth K, Jaeger E, Spain SL, Walther A, Barclay E, Martin L, Gorman M, Domingo E, Teixeira AS; CoRGI Consortium, Kerr D, Cazier JB, Niittymäki I, Tuupanen S, Karhu A, Aaltonen LA, Tomlinson IP, Farrington SM, Tenesa A, Prendergast JG, Barnetson RA, Cetnarskyj R, Porteous ME, Pharoah PD, Koessler T, Hampe J, Buch S, Schafmayer C, Tepel J, Schreiber S, Völzke H, Chang-Claude J, Hoffmeister M, Brenner H, Zanke BW, Montpetit A, Hudson TJ, Gallinger S; International Colorectal Cancer Genetic Association Consortium, Campbell H, Dunlop MG.Nat Genet. 2008 Dec;40(12):1426-35.
A mitotic recombination map proximal to the APC locus on chromosome 5q and assessment of influences on colorectal cancer risk.Howarth K, Ranta S, Winter E, Teixeira A, Schaschl H, Harvey JJ, Rowan A, Jones A, Spain S, Clark S, Guenther T, Stewart A, Silver A, Tomlinson I.BMC Med Genet. 2009 Jun 10;10:54.

Publications
Ng W, Loh AX, Teixeira AS, Pereira SP, Swallow DM. (2008) Genetic regulation of MUC1 alternative splicing in human tissues. Br J Cancer. 2008 Aug 26 [Epub ahead of print]
Reis CA, Teixeira A, David L (2004) Role of mucins in Helicobacter pylori adhesion to the gastric mucosa. Helicobacter 9(2):181 (letter to the editor)
Fowler JC, Teixeira AS, Vinall LE, Swallow DM (2003) Hypervariability of the membrane-associated mucin and cancer marker MUC1. Hum Genet 113(6):473-9
Silva F, Carvalho F, Peixoto A, Teixeira A, Almeida R, Reis C, Bravo LE, Realpe L, Correa P, David L (2003) MUC1 polymorphism confers increased risk for intestinal metaplasia in a Colombian population with chronic gastritis. Eur J Hum Genet 11(5):380-4
Teixeira A, David L, Reis CA, Costa J, Sobrinho-Simoes M (2002) Expression of mucins (MUC1, MUC2, MUC5AC, and MUC6) and type 1 Lewis antigens in cases with and without Helicobacter pylori colonization in metaplastic glands of the human stomach. J Pathol 197(1):37-43

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