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Class of 2000
Name
Lages Alves, Nuno
E-Mail
nalves@ibmc.up.pt
About the PhD
Field of Research
Immunology
Thesis Title
Visualizing IL-7 expresion in vivo (Pasteur Institute - Paris)
Abstract
Research Interest
My interest is focused on the function of the Thymus, the primary lymphoid organ responsible for the generation of T cells.

Epithelial cells within the thymus provide essential signals to promote T...
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Supervisor(s)
Prof. Dr. Rene van Lier
Co-Supervisor(s)
Prof. Dr. Fernando Arosa; Prof. Dr. Eric Eldering
University
Amsterdam
Laboratory
Academical Medical Center - Dep Immunology
Date of Thesis Defence
2007-01-24
After the PhD (Current Situation)
Position
Associate Research Scientist
Project
Ciência 2008
Institution
IBMC
View Institution website

Relevant Publications
Alves NL, Ester M.M. van Leeuwen, Ingrid A.M. Derks and René A.W. van Lier. Differential regulation of human IL-7 receptor alpha expression by IL-7 and TCR signaling .
J Immunol. 2008 Apr 15;180(8):5201-10
Alves NL, van Leeuwen EM, Remmerswaal EB, Vrisekoop N, Tesselaar K, Roosnek E, Ten Berge IJ, van Lier RA.
A New Subset of Human Naive CD8+ T Cells Defined by Low Expression of IL-7R{alpha}.
J Immunol. 2007 Jul 1;179(1):221-8.

Alves NL, Derks IA, Berk E, Spijker R, van Lier RA, Eldering E. “The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells”. Immunity 2006 Jun;24(6):703-16.
Alves NL, Arosa FA and van Lier RA. }3IL-21 Sustains CD28 Expression on IL-15-Activated Human Naive CD8+ T Cells}4.
J Immunol. 2005 Jul 15;175(2):755-62.

Alves NL, Hooibrink B, Arosa FA, van Lier RA. Blood. 2003 Oct 1;102(7):2541-6. Epub 2003 Jun 12. }3IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro.}4
Last Update
2013-03-14 15:06:28

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