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Class of 2000
Name
Corte-Real, Sofia
Nationality
Portuguese
E-Mail
scortereal@yahoo.com
1st Degree
Applied Chemistry
University (1st Degree)
UNL-FCT
About the PhD
Field of Research
Antibodies and Virology
Thesis Title
Intracellular Antibodies for Inhibition of Latency Associated Nuclear Antigen from Kaposi’s Sarcoma Associated Herpesvirus
Supervisor(s)
João Gonçalves
University
Faculty of Pharmacy University of Lisbon
Laboratory
URIA/CPM
City
Lisbon
Country
Portugal
Date of Thesis Defence
2005-06-27
After the PhD (Current Situation)
Position
R&D Director
Project
TechnoAntibodies
Institution
Technophage,SA
View Institution website
City
Lisbon
Country
Portugal

Relevant Publications
S. Corte-Real, L. Fonseca, C Barbas, Y Chang, P Moore, J. Gonçalves.
Intrabody-based mapping of Latency-Associated Nuclear Antigen from Kaposi’s Sarcoma-
Associated Herpesvirus show conserved epitopes for viral latency inhibition.
Virology: Research and Treatment 2010:2; 1-16
Book Chapter

Sofia Corte-Real, Frederico Aires da Silva and Joao Goncalves.
Chapter16- Development of Antibody Fragments for Therapeutic Applications
Castanho, M. / Santos, N. (eds.)
Peptide Drug Discovery and Development
Translational Research in Academia and Industry
Wiley-VCH Verlag GmbH & Co. KG (2011)

Aires da Silva F, Costa MJ, Corte-Real S, Goncalves J.

Cell type-specific targeting with sindbis pseudotyped lentiviral vectors displaying anti-CCR5 single-chain antibodies.
Hum Gene Ther. 2005 Feb;16(2):223-34.
Corte-Real S, Collins C, Aires da Silva F, Simas JP, Barbas CF 3rd, Chang Y, Moore P, Goncalves J.

Intrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells.
Blood. 2005 Dec 1;106(12):3797-802. Epub 2005 Aug 9.
S. Corte-Real , L.Fonseca and J. Gonçalves.
KSHV latency in transformed B- cells: The role of LANA1 as a therapeutic target.
Virology: Research and Treatment 2008:1; Review 1-6
Frederico Aires da Silva , Sofia Corte-Real and Joao Goncalves.
Recombinant antibodies as therapeutic agents. Pathways for modelling new biodrugs.
Biodrugs 2008;22(5):1
Last Update
2014-04-13 10:22:25
INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology