About the Program
Calendar 2018
Calendar 2017
Calendar 2016
Calendar 2015
Calendar 2014
Calendar 2013
Calendar 2012
Calendar 2011
The Students
Class of 2017
Class of 2016
Class of 2015
Class of 2014
Class of 2013
Class of 2012
Class of 2011
Class of 2010
Class of 2009
Class of 2008
Class of 2007
Class of 2006
Class of 2005
Class of 2004
Class of 2003
Class of 2002
Class of 2001
Class of 2000
Class of 1999
Class of 1997
Class of 1996
Research and Faculty
Coordinating Committee
Module Coordinators
PhD Degrees Completed
Events and Highlights
All Time GABBAs
Reserved Area
Forgot your password?
Class of 2000
Santos, Susana G.
Master Degree
Biomedical Sciences
About the PhD
Field of Research
Thesis Title
Inflammatory Response to Biomaterials
Dr. Fernando A. Arosa, and Dr. Simon J. Powis
ICBAS - University of Porto
IBMC, ICBAS - University of Porto, and CLS - University of Dundee
Date of Thesis Defence

Relevant Publications
Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation. (2004)
Santos SG, Powis SJ, Arosa FA.
J Biol Chem, 279:53062-70
View Publication
Lack of tyrosine 320 impairs spontaneous endocytosis and enhances release of HLA-B27 molecules. (2006)
Santos SG, Antoniou AN, Sampaio P, Powis SJ, Arosa FA.
J Immunol, 176:2942-9.
View Publication
Major histocompatibility complex class I-ERp57-tapasin interactions within the peptide-loading complex. (2007)
Santos SG, Campbell EC, Lynch S, Wong V, Antoniou AN, Powis SJ
J Biol Chem, 282:17587-93
View Publication
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. (2008)
Ananieva O, Darragh J, Johansen C, Carr JM, McIlrath J, Park JM, Wingate A, Monk CE, Toth R, Santos SG, Iversen L, Arthur JS.
Nat Immunol, 9:1028-36
View Publication
Induction of HLA-B27 heavy chain homodimer formation after activation in dendritic cells. (2008)
Santos SG, Lynch S, Campbell EC, Antoniou AN, Powis SJ.
Arthritis Res Ther, 10:R100. [Epub ahead of print]
View Publication

Open conformers: the hidden face of MHC-I molecules.
Arosa FA, Santos SG, Powis SJ.
Trends Immunol, 28:115-23
View Publication
ERp57 interacts with conserved cysteine residues in the MHC class I peptide-binding groove.
Antoniou AN, Santos SG, Campbell EC, Lynch S, Arosa FA, Powis SJ.
FEBS Lett, 581:1988-92
View Publication

The responsibility for this page contents is entirely of the student/alumnus.
Program financially supported by
the National Foundation for
Science and Technology