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Class of 2001
Name
Patarrão, Rita
E-Mail
rita.patarrao@nms.unl.pt
1st Degree
Biochemistry
About the PhD
Field of Research
Diabetes
Thesis Title
The relevance of the Hepatic Insulin Sensitizing Substance (HISS) on diseases associated with insulin resistance
Abstract
Insulin action is associated with the release of the Hepatic Insulin Sensitizing Substance (HISS), which enhances peripheral glucose uptake. In the fed state, HISS release is maximal, decreasing with the duration of fasting....
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Supervisor(s)
Prof. Doutora M. Paula Macedo, Prof. Doutor W. Wayne Lautt
University
FCM-UNL, Univ. of Manitoba
Laboratory
Physiology and Pharmacology
Date of Thesis Defence
2010-12-16
After the PhD (Current Situation)
Position
Post-doc, Biochemistry Professor
Institution
NMS-UNL
City
Lisbon
Country
Portugal

Relevant Publications
Ana B. Fernandes, Rita S. Patarrão, Paula A. Videira and M. Paula Macedo, Understanding postprandial glucose clearance by peripheral organs: the role of the hepatic parasympathetic system. J Neuroendocrinol, 23(12): 1288-1295 (2011)
Ricardo A. Afonso, Ana B. Fernandes, Celina Santos, Dário Ligeiro, Inês S. Lima, Rita S. Patarrão, Paula A. Videira, Jorge Caldeira and M. Paula Macedo, Postprandial insulin resistance in zucker diabetic fatty rats is associated with parasympathetic-no axis deficiencies. J Neuroendocrinol. 24: 1346-1355 (2012).
Rita S. Patarrão, W. Wayne Lautt, Ricardo A. Afonso, Rogério T. Ribeiro, Ana B. Fernandes, José M. Boavida and M. Paula Macedo, Postprandial but not fasting insulin resistance is an early identifier of dysmetabolism in overweight subjects. Can J Physiol Pharmacol. 90: 923-931 (2012).
Macedo MP, Lima IS, Gaspar JM, Afonso RA, Patarrão RS, Kim YB & Ribeiro RT, Risk of postprandial insulin resistance: The liver/vagus rapport. Rev Endocr Metab Disord. 15 (1): 67-77 (2014)
N. Duarte, I. C. Coelho, Rita S. Patarrão, J. I. Almeida, C. Penha-Gonçalves and M. P. Macedo, How inflammation impinges on NAFLD: a role for Kupffer cells. Biomed Res Int. (2015)
Rita S. Patarrão, W. Wayne Lautt and M. Paula Macedo, Acute glucagon induces postprandial peripheral insulin resistance. PLoS One, 10(5): 1-16 (2015).
Rita S. Patarrão, W. Wayne Lautt, Maria P. Guarino, Ricardo A. Afonso, Rogério T. Ribeiro, Ana B. Fernandes, José M. Boavida and M. Paula Macedo, Meal-induced insulin sensitisation and its parasympathetic regulation in humans. Can J Physiol Pharmacol, 86: 880-888 (2008).
Rita S. Patarrão, W. Wayne Lautt, Maria P. Guarino, Ricardo A. Afonso, Rogério T. Ribeiro, Ana B. Fernandes, José M. Boavida and M. Paula Macedo, A new technique to assess insulin sensitivity in humans: the rapid insulin sensitivity test (RIST). Proc West Pharmacol Soc, 50: 105-109 (2007).
Ricardo A. Afonso, Rogério T. Ribeiro, Ana B. Fernandes, Rita S. Patarrão and M. Paula Macedo. Hepatic-dependent and independent insulin action are impaired in the obese Zucker rat model. Obesity, 15: 314-321 (2007).
Celina Santos, Ricardo A. Afonso, Maria P. Guarino, Rita S. Patarrão, Ana B. Fernandes, Maria P. Macedo and Jorge Caldeira, In vitro nitrosation of insulin A and B-chains. Eur J Mass Spectrom, 12: 331-338 (2006).
Ricardo A. Afonso, Rita S. Patarrão, M. Paula Macedo and M. Mota Carmo, Carvedilol action is dependent on endogenous production of nitric oxide. Am J Hyper, 19: 419-425 (2005).
Patarrão, R. S., Macedo, M. P. and Mota Carmo, M., Hepatic metabolic effects of norepinephrine are potentiated by nitric oxide. Proc West Pharmacol Soc, 44: 23 (2001).

Publications
Pinto P, Barbara C, Montserrat JM, Patarrão RS, Guarino MP, Carmo MM, Macedo MP, Martinho C, Dias R & Gomes MJ, Effects of CPAP on nitrate and norepinephrine levels in severe and mild-moderate sleep apnea. BMC Pulm Med. 13, 13 (2013).
Last Update
2017-10-11 11:55:09

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