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Class of 2002
Name
Beltrão, Pedro
Nationality
Portuguese
E-Mail
pedrobeltrao@gmail.com
1st Degree
Biochemistry
University (1st Degree)
Universidade de Coimbra
About the PhD
Field of Research
bioinformatics, evolution, systems biology
Thesis Title
Computational Tools for the Study of Cellular Networks
Supervisor(s)
Luis Serrano
Co-Supervisor(s)
Manuel Santos
University
Aveiro, Portugal
Laboratory
Serrano Lab, EMBL
City
Heidelberg
Country
Germany
Date of Thesis Defence
2007-09-21
After the PhD (Current Situation)
Position
Postdoc (Lim lab and Krogan lab)
Project
Evolution of signaling pathways in fungi
Institution
UCSF
City
San Francisco
Country
USA

Relevant Publications
Beltrao P, Trinidad JC, Fiedler D, Roguev A, Lim WA, Shokat KM, Burlingame AL, Krogan NJ “Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species” PLoS Biol. 2009 Jun 16;7(6):e1000134
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Beltrao P, Cagney C, Krogan NJ “Quantitative Genetic Interactions Reveal Layers of Biological Modularity” Cell. 2010 May 28;141(5):739-45
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Kapitzky L, Beltrao P, Berens TJ, Gassner N, Zhou C, Wüster A, Wu J, Babu M,Elledge SJ,Toczyski D,Lokey RS, Krogan NJ “Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action” Mol Syst Biol., 2010 Dec 21;6:451
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Nichols RJ, Sen S, Choo YJ, Beltrao P, Zietek M, Chaba R, Lee S, Kazmierczak K, Lee K, Wong A, Shales M, Lovett S, Winkler M, Krogan NJ, Typas A, Gross CA “Phenotypic Landscape of a Bacterial Cell” Cell, 2011 Jan 7;144(1):143-56
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Beltrao P, Serrano L.Specificity and evolvability in eukaryotic protein interaction networks. PLoS Comput Biol. 2007 Feb 16;3(2):e25. Epub 2006 Dec 28.
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Isalan M, Lemerle C, Michalodimitrakis K, Horn C, Beltrao P, Raineri E, Garriga-Canut M, Serrano L.Evolvability and hierarchy in rewired bacterial gene networks. Nature. 2008 Apr 17;452(7189):840-5.
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Publications
Fernandez-Ballester G, Beltrao P, Gonzalez JM, Song YH, Wilmanns M, Valencia A, Serrano L. “Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions” J Mol Biol. 2009 May 15;388(4):902-16. Epub 2009 Mar 24
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Encinar JA, Fernandez-Ballester G, Sánchez IE, Hurtado-Gomez E, Stricher F, Beltrao P, Serrano L. “ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs” Bioinformatics. 2009 Sep 15;25(18):2418-24
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Lefebvre C, Rajbhandari P, Alvarez MJ, Bandaru P, Lim WK, Sato M, Wang K, Sumazin P, Kustagi M, Bisikirska BC, Basso K, Beltrao P, Krogan N, Gautier J, Dalla-Favera R, Califano A. “A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers” Mol Syst Biol. 2010 Jun 8;6:377
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Massey SE, Moura G, Beltrão P, Almeida R, Garey JR, Tuite MF, Santos MA. Comparative evolutionary genomics unveils the molecular mechanism of reassignment of the CTG codon in Candida spp. Genome Res. 2003 Apr;13(4):544-57.
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Beltrao P, Serrano L. Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions. PLoS Comput Biol. 2005 Aug;1(3):e26. Epub 2005 Aug 12.
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INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology