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Class of 2002
Name
Albuquerque, Sónia
Nationality
Portuguese
E-Mail
sonialbuquerque@mail.pt
1st Degree
Biology
About the PhD
Field of Research
Genetics of Malaria
Thesis Title
Characterization of host cell response to Plasmodium infection: identification of hepatocyte genes involved in parasite development
Abstract
Malaria is caused by the protozoan parasite Plasmodium and is one of the most prevalent infectious diseases worldwide. Plasmodium sporozoites invade hepatocytes, initiating the hepatic stage of malaria within minutes after...
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Supervisor(s)
Dr. Maria Manuel Mota
Co-Supervisor(s)
Dr. Maria de Sousa
University
ICBAS
Laboratory
IGC, IMM
City
Oeiras, Lisbon
Country
Portugal
Date of Thesis Defence
2007-03-26
After the PhD (Current Situation)
Position
Clinical Research Associate
Project
Clinical Trials (Oncology, Cardiology, Autoimmune disease, etc.)
Institution
SIRO Clinpharm (employee company)
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City
Barcelona
Country
Spain

Relevant Publications
Albuquerque SS, Carret C, Grosso AR, Tarun AS, Peng X, Kappe SH, Prudêncio M, Mota MM. (2009) Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events. BMC Genomics Jun 17;10:270
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Publications
Epiphanio S, Mikolajczak SA, Gonçalves LA, Pamplona A, Portugal S, Albuquerque S, Goldberg M, Rebelo S, Anderson DG, Akinc A, Vornlocher HP, Kappe SH, Soares MP, Mota MM. (2008) Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. Cell Host Microbe May 15;3(5):331-8
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Leirião P, Albuquerque SS, Corso S, van Gemert GJ, Sauerwein RW, Rodriguez A, Giordano S, Mota MM. 2005. HGF/MET signalling protects Plasmodium-infected host cells from apoptosis. Cell Microbiol. 7:603-9.
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Leirião P, Rodrigues CD, Albuquerque SS, Mota MM. 2004. Survival of protozoan intracellular parasites in host cells. EMBO Rep. 5:1142-7.

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INSTITUTIONS INVOLVED
Program financially supported by
the National Foundation for
Science and Technology