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| Name |
| Nóbrega, Cláudia |
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| Nationality |
| Portuguese |
| E-Mail |
| crnobrega@gmail.com |
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| 1st Degree |
| Biochemistry |
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| University (1st Degree) |
| Faculty of Sciences, University of Lisbon |
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| About the PhD |
| Field of Research |
| Immunology of Infection |
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| Thesis Title |
| Infection of the thymus by mycobacteria: potential impact on the immune response to infection |
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| Supervisor(s) |
| Margarida Correia-Neves |
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| Co-Supervisor(s) |
| Rui Appelberg |
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| University |
| Instituto de Ciencias Biomédicas Abel Salazar (ICBAS), University of Porto |
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| Laboratory |
| Infection and Immunology Laboratory, Institute for Molecular and Cell Biology (IBMC) |
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| City |
| Porto |
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| Country |
| Portugal |
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| Date of Thesis Defence |
| 2009-06-01 |
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| After the PhD (Current Situation) |
| Position |
| Posdoctoral fellow |
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| Project |
| The role of regulatory T cells on immune reconstitution of HIV-infected individuals and on the development of malignancies related to immunosuppression |
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| Institution |
| Life and Health Sciences Research Institute |
| View Institution website |
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| City |
| Braga |
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| Country |
| Portugal |
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| Relevant Publications |
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Dissemination of mycobacteria to the thymus renders newly generated T cells tolerant to the invading pathogen
C. Nobrega, S. Roque, C. Nunes-Alves, A. Coelho, I. Medeiros, A. G. Castro, R. Appelberg, M. Correia-Neves
Journal of Immunology, 2010, 184: 351
doi:10.4049/jimmunol.0902152 |
| View Publication |
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A case-control study on the diagnostic potential of multi-antigen serological tests for tuberculosis
R. Duarte, A. Afonso, C. Ferreira, S. Roque, O. Vasconcelos, R. Sarmento-Castro, M. Tavares, C. Caldas, R. Greenwald, K. Lyashchenko, M. Correia-Neves, C. Nobrega
Archives of Clinical Microbiology, 2012, 3(2): 1-5
doi: 10.3823/249 |
| View Publication |
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T cells home to the thymus and control infection
C. Nobrega*, C. Nunes-Alves*, B. Cerqueira-Rodrigues, S. Roque, P. Barreira-Silva, S. M. Behar, M. Correia-Neves
Journal of Immunology, 2013, 190:1646
doi:10.4049/jimmunol.1202412 |
| View Publication |
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High percentage of regulatory CD4+ T cells associates with worse immune reconstitution in HIV-infected patients
A. Horta*, C. Nobrega*, P. Amorim-Machado, V. Coutinho-Teixeira, P. Barreira-Silva, S. Boavida, P. Costa, R. Sarmento-Castro, A. Gil Castro, M. Correia-Neves
PLoS ONE, 2013, 8(2):e257336
doi:10.1371/journal.pone.005733 |
| View Publication |
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Tolerance has its limits: how the thymus copes with infection
C. Nunes-Alves, C. Nobrega, S. Behar, M. Correia-Neves
Trends in immunology (2013), 34(10):502-510
doi 10.1016/j.it.2013.06.004 |
| View Publication |
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Longitudinal evaluation of regulatory T-cell dynamics on HIV-infected individuals during the first 2 years of therapy
C. Nobrega, A. Horta, V. Coutinho-Teixeira, A. Martins-Ribeiro, A. Baldaia, R. Rb-Silva, C. L. Santos, R. Sarmento-Castro, M. Correia-Neves
AIDS (2016), 30: 1175-85
doi:10.1097/QAD.0000000000001074 |
| View Publication |
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Toxoplasmosis-associated immune reconstitution inflammatory syndrome involving the central nervous system (CNS-IRIS): a case report with longitudinal analysis of T cell subsets
R. Rb-Silva*, C. Nobrega*, E. Reiriz, S. Almeida, R. Sarmento-Castro, M. Correia-Neves, A. Horta
BMC Infectious Disease (2017), 17: 66.
DOI 10.1186/s12879-016-2159-x |
| View Publication |
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The thymus as a target for mycobacterial infections
C. Nobrega, P.-J. Cardona, S. Roquea, P. Pinto do Ó, R. Appelberg, M. Correia-Neves
Microbes and Infection, 2007, 9 (14-15): 1521 |
| View Publication |
| Publications |
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Environmental Enrichment does not Compromise the Immune Response in Mice Chronically Infected with Mycobacterium avium
A. Olsson, A. Costa, C. Nobrega, S. Roque, M. Correia-Neves
Scandinavian Journal of Immunology, 2010, 71(4): 249
doi: 10.1111/j.1365-3083.2010.02371.x |
| View Publication |
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Interplay between depressive-like behavior and the immune system in an animal model of prenatal dexamethasone administration
S. Roque, T. Gil Oliveira, C. Nobrega, P. Barreira-Silva, C. Nunes-Alves, N. Sousa, J. Almeida Palha, M. Correia-Neves
Frontiers in Behavioral Neurosciences, 2011, 5: 4
doi: 10.3389/fnbeh.2011.00004 |
| View Publication |
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Lipoarabinomannan mannose caps do not affect mycobacterial virulence and immunogenicity in experimental animal models of infection
A. Afonso-Barroso, S.O. Clark, A. Williams, G.T. Rosa, C. Nobrega, S. Silva-Gomes, S. Vale-Costa, R. Ummels, N. Stoker, F.M. Zadeh, P. van der Ley, B.J. Appelmelk, G. Puzo, J. Nigou, J. Geurtsen, R. Appelberg
Cellular Microbiology, 2013, 15(4): 660
doi:10.1111/cmi.12065 |
| View Publication |
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A bacteriophage detection tool for viability assessment of Salmonella cells
E. Fernandes, V. Martins, C. Nobrega, C. M. Carvalho, F. A. Cardoso, S. Cardoso, J. Dias, D. Deng, L. D. Kluskens, P. P. Freitas, J. Azeredo
Biosensors and Bioelectronics (2014) 15:239-246
doi: 10.1016/j.bios.2013.08.053
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| View Publication |
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IL-10 Underlies Distinct Susceptibility of BALB/c and C57BL/6 Mice to Mycobacterium avium Infection and Influences Efficacy of Antibiotic Therapy
S. Roque, C. Nobrega, R. Appelberg, M. Correia-Neves
The Journal of Immunology, 2007, 178: 8028 |
| View Publication |
| Last Update |
| 2017-10-09 11:38:20 |
| The responsibility for this page contents is entirely of the student/alumnus. |
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Program financially supported by
the National Foundation for
Science and Technology
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