About the Program
Calendar 2017
Calendar 2016
Calendar 2015
Calendar 2014
Calendar 2013
Calendar 2012
Calendar 2011
The Students
Class of 2016
Class of 2015
Class of 2014
Class of 2013
Class of 2012
Class of 2011
Class of 2010
Class of 2009
Class of 2008
Class of 2007
Class of 2006
Class of 2005
Class of 2004
Class of 2003
Class of 2002
Class of 2001
Class of 2000
Class of 1999
Class of 1997
Class of 1996
Research and Faculty
Coordinating Committee
Module Coordinators
PhD Degrees Completed
Events and Highlights
Reserved Area
Forgot your password?
Class of 2004
Nóbrega, Cláudia
1st Degree
About the PhD
Field of Research
Immunology of Infection
Thesis Title
Infection of the thymus by mycobacteria: potential impact on the immune response to infection
Margarida Correia-Neves
Rui Appelberg
Instituto de Ciencias Biomédicas Abel Salazar (ICBAS), University of Porto
Infection and Immunology Laboratory, Institute for Molecular and Cell Biology (IBMC)
Date of Thesis Defence
After the PhD (Current Situation)
Posdoctoral fellow
Characterization of T cells in HIV+ patients co-infected with tuberculosis
Life and Health Sciences Research Institute
View Institution website

Relevant Publications
Dissemination of mycobacteria to the thymus renders newly generated T cells tolerant to the invading pathogen
C. Nobrega, S. Roque, C. Nunes-Alves, A. Coelho, I. Medeiros, A. G. Castro, R. Appelberg, M. Correia-Neves
Journal of Immunology, 2010, 184: 351
View Publication
A case-control study on the diagnostic potential of multi-antigen serological tests for tuberculosis
R. Duarte, A. Afonso, C. Ferreira, S. Roque, O. Vasconcelos, R. Sarmento-Castro, M. Tavares, C. Caldas, R. Greenwald, K. Lyashchenko, M. Correia-Neves, C. Nobrega
Archives of Clinical Microbiology, 2012, 3(2): 1-5
doi: 10.3823/249
View Publication
T cells home to the thymus and control infection
C. Nobrega*, C. Nunes-Alves*, B. Cerqueira-Rodrigues, S. Roque, P. Barreira-Silva, S. M. Behar, M. Correia-Neves
*These authors have equally contributed to this work
Journal of Immunology, 2013, 190:1646
High percentage of regulatory CD4+ T cells associates with worse immune reconstitution in HIV-infected patients
A. Horta*, C. Nobrega*, P. Amorim-Machado, V. Coutinho-Teixeira, P. Barreira-Silva, S. Boavida, P. Costa, R. Sarmento-Castro, A. Gil Castro, M. Correia-Neves
*These authors have equally contributed to this work
PLoS ONE, 2013, 8(2):e257336
Tolerance has its limits: how the thymus copes with infection
C. Nunes-Alves, C. Nobrega, S. Behar, M. Correia-Neves
Trends in Immunology, 2013
doi 10.1016/j.it.2013.06.004
The thymus as a target for mycobacterial infections
C. Nobrega, P.-J. Cardona, S. Roquea, P. Pinto do Ó, R. Appelberg, M. Correia-Neves
Microbes and Infection, 2007, 9 (14-15): 1521
View Publication

Environmental Enrichment does not Compromise the Immune Response in Mice Chronically Infected with Mycobacterium avium
A. Olsson, A. Costa, C. Nobrega, S. Roque, M. Correia-Neves
Scandinavian Journal of Immunology, 2010, 71(4): 249
doi: 10.1111/j.1365-3083.2010.02371.x
View Publication
Interplay between depressive-like behavior and the immune system in an animal model of prenatal dexamethasone administration
S. Roque, T. Gil Oliveira, C. Nobrega, P. Barreira-Silva, C. Nunes-Alves, N. Sousa, J. Almeida Palha, M. Correia-Neves
Frontiers in Behavioral Neurosciences, 2011, 5: 4
doi: 10.3389/fnbeh.2011.00004
View Publication
Lipoarabinomannan mannose caps do not affect mycobacterial virulence and immunogenicity in experimental animal models of infection
A. Afonso-Barroso, S.O. Clark, A. Williams, G.T. Rosa, C. Nobrega, S. Silva-Gomes, S. Vale-Costa, R. Ummels, N. Stoker, F.M. Zadeh, P. van der Ley, B.J. Appelmelk, G. Puzo, J. Nigou, J. Geurtsen, R. Appelberg
Cellular Microbiology, 2013, 15(4): 660
A bacteriophage detection tool for viability assessment of Salmonella cells
E. Fernandes, V. Martins, C. Nobrega, C. M. Carvalho, F. A. Cardoso, S. Cardoso, J. Dias, D. Deng, L. D. Kluskens, P. P. Freitas, J. Azeredo
Biosensors and Bioelectronics (Accepted for publication)
IL-10 Underlies Distinct Susceptibility of BALB/c and C57BL/6 Mice to Mycobacterium avium Infection and Influences Efficacy of Antibiotic Therapy
S. Roque, C. Nobrega, R. Appelberg, M. Correia-Neves
The Journal of Immunology, 2007, 178: 8028
View Publication
Program financially supported by
the National Foundation for
Science and Technology