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Class of 2005
Name
Rebocho, Ana Paula
E-Mail
apd42@cam.ac.uk
1st Degree
Biology
University (1st Degree)
Universidade de Aveiro
About the PhD
Field of Research
Signal Transduction in Cancer
Thesis Title
Cellular Signalling by ARAF
Abstract

Supervisor(s)
Professor Richard Marais
Co-Supervisor(s)
Professor Christopher Marshall
University
University of London
Laboratory
Institute of Cancer Research
City
London
Date of Thesis Defence
2010-11-26
After the PhD (Current Situation)
Position
Research Associate
Institution
University of Cambridge - Department of Biochemistry
View Institution website
City
Cambridge
Country
United Kingdom

Relevant Publications
Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia.
Cancer Cell
Packer LM, Rana S, Hayward R, O'Hare T, Eide CA, Rebocho A, Heidorn S, Zabriskie MS, Niculescu-Duvaz I, Druker BJ, Springer C, Marais R.
View Publication
ARAF acts as a scaffold to stabilise BRAF:CRAF heterodimers. Oncogene
Rebocho AP and Marais R.
View Publication

Publications
Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations.
BMC Cancer
Preto A, Gonçalves J, Rebocho AP, Figueiredo J, Meireles AM, Rocha AS, Vasconcelos HM, Seca H, Seruca R, Soares P, Sobrinho-Simões M
View Publication
New insight puts CRAF in sight as a therapeutic target.
Cancer Discovery
Rebocho AP, Marais R.
View Publication
Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines.
Thyroid
Meireles AM, Preto A, Rocha AS, Rebocho AP, Máximo V, Pereira-Castro I, Moreira S, Feijão T, Botelho T, Marques R, Trovisco V, Cirnes L, Alves C, Velho S, Soares P, Sobrinho-Simões M.
A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation.
Virchows Arch.
Preto A, Moutinho C, Velho S, Oliveira C, Rebocho AP, Figueiredo J, Soares P, Lopes JM, Seruca R.
PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.
J Clin Endocrinol Metab.
Castro P, Rebocho AP, Soares RJ, Magalhães J, Roque L, Trovisco V, Vieira de Castro I, Cardoso-de-Oliveira M, Fonseca E, Soares P, Sobrinho-Simões M.

[more publications]
Last Update
2013-12-18 23:10:54

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