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| Name |
| Rebocho, Ana Paula |
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| E-Mail |
| apd42@cam.ac.uk |
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| 1st Degree |
| Biology |
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| University (1st Degree) |
| Universidade de Aveiro |
|
| About the PhD |
| Field of Research |
| Signal Transduction in Cancer |
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| Thesis Title |
| Cellular Signalling by ARAF |
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| Abstract |
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| Supervisor(s) |
| Professor Richard Marais |
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| Co-Supervisor(s) |
| Professor Christopher Marshall |
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| University |
| University of London |
|
| Laboratory |
| Institute of Cancer Research |
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| City |
| London |
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| Date of Thesis Defence |
| 2010-11-26 |
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| After the PhD (Current Situation) |
| Position |
| Research Associate |
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| Institution |
| University of Cambridge - Department of Biochemistry |
| View Institution website |
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| City |
| Cambridge |
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| Country |
| United Kingdom |
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| Relevant Publications |
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Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia.
Cancer Cell
Packer LM, Rana S, Hayward R, O'Hare T, Eide CA, Rebocho A, Heidorn S, Zabriskie MS, Niculescu-Duvaz I, Druker BJ, Springer C, Marais R. |
| View Publication |
|
ARAF acts as a scaffold to stabilise BRAF:CRAF heterodimers. Oncogene
Rebocho AP and Marais R. |
| View Publication |
| Publications |
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Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations.
BMC Cancer
Preto A, Gonçalves J, Rebocho AP, Figueiredo J, Meireles AM, Rocha AS, Vasconcelos HM, Seca H, Seruca R, Soares P, Sobrinho-Simões M |
| View Publication |
|
New insight puts CRAF in sight as a therapeutic target.
Cancer Discovery
Rebocho AP, Marais R. |
| View Publication |
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Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines.
Thyroid
Meireles AM, Preto A, Rocha AS, Rebocho AP, Máximo V, Pereira-Castro I, Moreira S, Feijão T, Botelho T, Marques R, Trovisco V, Cirnes L, Alves C, Velho S, Soares P, Sobrinho-Simões M.
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A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation.
Virchows Arch.
Preto A, Moutinho C, Velho S, Oliveira C, Rebocho AP, Figueiredo J, Soares P, Lopes JM, Seruca R.
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PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.
J Clin Endocrinol Metab.
Castro P, Rebocho AP, Soares RJ, Magalhães J, Roque L, Trovisco V, Vieira de Castro I, Cardoso-de-Oliveira M, Fonseca E, Soares P, Sobrinho-Simões M.
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[more publications]
| More Publications |
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BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas.
Virchows Arch.
Soares P, Trovisco V, Rocha AS, Feijão T, Rebocho AP, Fonseca E, Vieira de Castro I, Cameselle-Teijeiro J, Cardoso-Oliveira M, Sobrinho-Simões M.
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| Last Update |
| 2013-12-18 23:10:54 |
| The responsibility for this page contents is entirely of the student/alumnus. |
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Program financially supported by
the National Foundation for
Science and Technology
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