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Class of 2005
Raposo, R. André
1st Degree
University (1st Degree)
University of Coimbra
About the PhD
Field of Research
HIV-1 Virology / Immnuology
Thesis Title
T cell activation-induced soluble factors trigger CD4 down-regulation in human macrophages: consequences for HIV-1 infection
Professor William James
University of Oxford
Sir William Dunn School of Pathology
United Kingdom
Date of Thesis Defence
After the PhD (Current Situation)
Research Scientist
HIV-1 latency and Host Restriction Factors
The George Washington University
View Institution website
Washington, DC

Relevant Publications
Proteomic-Based Identification of CD4-Interacting Proteins in Human Primary Macrophages
Raposo RA et al., 2011: PLoS ONE 6(4): e18690
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Protein Kinase C and NF-kB-Dependent CD4 Downregulation in Macrophages Induced by T Cell-Derived Soluble Factors: Consequences for HIV-1 Infection.
Raposo RA et al., 2011: J Immunol 187(2): 748-59
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Increased expression of intrinsic antiviral genes in HLA-B*57-positive individuals
Raposo RA et al., 2013: J Leukoc Biol, jlb.0313150; doi:10.1189/jlb.0313150
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Effects of Cellular Activation on Anti-HIV-1 Restriction Factor Expression Profile in Primary Cells
Raposo RA et al., 2013, J. Virol. published ahead of print 21 August 2013 , doi:10.1128/JVI.02128-13
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Expression profile of host restriction factors in HIV-1 elite controllers
Abdel-Mohsen M, Raposo RA et al., Retrovirology 2013, 10:106 (16 October 2013)
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Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo
Raposo RA, Abdel-Mohsen M, Deng X, Hecht FM, Pilcher CD, Pillai SK and Nixon DF.
J. Virol. published ahead of print 16 July 2014 , doi:10.1128/JVI.01771-14
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Test, treat, and cure.
Nixon DF, Simon GL, Raposo RA.
J Acquir Immune Defic Syndr. 2015 Jan 1;68(1):e9-10. doi: 10.1097/QAI.0000000000000385.
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Antiviral gene expression in psoriasis.
Raposo RA, Gupta R, Abdel-Mohsen M, Dimon M, Debbaneh M, Jiang W, York VA, Leadabrand KS, Brown G, Malakouti M, Arron S, Kuebler PJ, Wu JJ, Pillai SK, Nixon DF, Liao W.
J Eur Acad Dermatol Venereol. 2015 Mar 23. doi: 10.1111/jdv.13091. [Epub ahead of print]
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Modulating APOBEC expression enhances DNA vaccine immunogenicity.
Almeida RR, Raposo RA, Caroline Coirada F, da Silva JR, de Souza Ferreira LC, Kalil J, Nixon DF, Cunha-Neto E.
Immunol Cell Biol. 2015 May 8. doi: 10.1038/icb.2015.53.
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Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial.
Kuebler PJ, Mehrotra ML, McConnell JJ, Holditch SJ, Shaw BI, Tarosso LF, Leadabrand KS, Milush JM, York VA, Raposo RA, Cheng RG, Eriksson EM, McMahan V, Glidden DV, Shiboski S, Grant RM, Nixon DF, Kallás EG.
Proc Natl Acad Sci U S A. 2015 Jun 22. pii: 201501443. [Epub ahead of print]
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Influence of HAART on Alternative Reading Frame Immune Responses over the Course of HIV-1 Infection.
Champiat S, Raposo RA, et al., 2012: PLoS ONE 7(6): e39311
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T Cells Target APOBEC3 Proteins in HIV-1-infected Humans and SIV-infected Indian Rhesus Macaques
Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, Hecht FM, Ostrowski MA, Sacha JB, Nixon DF.
J Virol. 2013 Mar 27. [Epub ahead of print]
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LINE-1 Retrotransposable Element DNA Accumulates in HIV-1-infected Cells
J Virol. 2013, Oct 2. [Epub ahead of print]
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Last Update
2015-04-07 02:49:47

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